4'-Mercaptoacetanilide → N-[4-(4-Methyl-2-nitro-phenylsulfanyl)-phenyl]-acetamide

反応式

[CH3:1][C:2]1[CH:7]=[CH:6][C:5](OS(C(F)(F)F)(=O)=O)=[C:4]([N+:16]([O-:18])=[O:17])[CH:3]=1.[SH:19][C:20]1[CH:25]=[CH:24][C:23]([NH:26][C:27](=[O:29])[CH3:28])=[CH:22][CH:21]=1>>[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([S:19][C:20]2[CH:21]=[CH:22][C:23]([NH:26][C:27](=[O:29])[CH3:28])=[CH:24][CH:25]=2)=[C:4]([N+:16]([O-:18])=[O:17])[CH:3]=1

参加物

反応物 2

HCID 707774'-Mercaptoacetanilide

HCID 713468894-Methyl-2-nitrophenyl trifluoromethanesulfonate

生成物 1

HCID 66808408N-[4-(4-Methyl-2-nitro-phenylsulfanyl)-phenyl]-acetamide収率 98%

実験手順

The product from Example 9a (1 g, 3.51 mmol) was reacted with N-(4-mercapto-phenyl)-acetamide (0.65 g, 351 mmol) for 18 h following the procedure from Example 9b giving the title compound (1.04 g, 98%).

出典と根拠

ORDレコード: ord-73aef8784b6e4213b3443ec303d3a1c2
出典データセット: uspto-grants-2012_08
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08236950B2

反応ノート

読み込み中…