関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Cesium carbonate | HCID 10796 | — |
| 反応物 | 4-Chloro-3-nitrophenol | HCID 69127 | — |
| 反応物 | 4'-Mercaptoacetanilide | HCID 70777 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | N-[4-(4-Hydroxy-2-nitro-phenylsulfanyl)-phenyl]-acetamide | HCID 67249335 | 100% |
反応手順
A mixture of 3-nitro-4-chloro phenol (1.59 g, 8.97 mmol), 4-acetamidothiophenol (2 g, 10.76 mmol) and cesium carbonate (7.0 g, 21.53 mmol) in DMF (20 mL) was heated 2.5 h at 100° C. The mixture was cooled, poured onto ice and the resulting solid is collected by filtration and dried under vacuum the title compound leaving a yellow solid (2.7 g, 100%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08236950B2 |
|---|
| 出典データセット | uspto-grants-2012_08 |
|---|
| ORD ID | ord-911e024ca10e470ab9d11f43a6db3809 |
|---|
| 出典メモ | uspto-grants-2012_08 |
|---|
