Dimethylformamide dimethyl acetal → HCID 66808327、化合物

HRID 883980ノート

反応式

HRID 883980 の反応式
[NH2:1][C:2]1[C:7]([C:8]#[N:9])=[CH:6][C:5]([C:10]#[N:11])=[C:4]([CH3:12])[N:3]=1.CO[CH:15](OC)[N:16]([CH3:18])[CH3:17]>C1(C)C=CC=CC=1>[C:8]([C:7]1[C:2]([N:1]=[CH:15][N:16]([CH3:18])[CH3:17])=[N:3][C:4]([CH3:12])=[C:5]([C:10]#[N:11])[CH:6]=1)#[N:9]

参加物

4

反応物 2

HCID 78373Dimethylformamide dimethyl acetalHCID 27867262-Amino-6-methylpyridine-3,5-dicarbonitrile

生成物 1

HCID 66808327HCID 66808327、化合物収率 94%

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

A solution of 2-Amino-6-methyl-pyridine-3,5-dicarbonitrile (0.158 g, 1.0 mmol) and N,N-Dimethylformamide dimethyl acetal (0.119 g, 1.0 mmol) in toluene (10 mL) was heated at reflux for 6 hours. After cooling to room temperature, the solution was concentrated under vacuum to provide the title compound as a brown solid (0.2 g, 94%).

後処理

  1. temperatureat reflux for 6 hours
  2. concentrationthe solution was concentrated under vacuum

出典と根拠

ORDレコード
ord-85a5cbe9840641139fb5fac0b6aab6d5
出典データセット
uspto-grants-2012_08
特許番号
US08236950B2

反応ノート

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