4-Methyl-5-phenyl-2-oxazolidinone, (4S,5R)- → {3-[4-Bromo-2-((4S,5R)-4-methyl-2-oxo-5-phenyl-oxazolidin-3-ylmethyl)-phenoxy]-phenyl}-acetic acid ethyl ester

HRID 885281

反応式

HRID 885281 の反応式
[CH2:1]([O:3][C:4](=[O:22])[CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([O:12][C:13]2[CH:18]=[CH:17][C:16]([Br:19])=[CH:15][C:14]=2[CH2:20]Br)[CH:7]=1)[CH3:2].[CH3:23][C@H:24]1[C@@H:28]([C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)[O:27][C:26](=[O:35])[NH:25]1>>[CH2:1]([O:3][C:4](=[O:22])[CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([O:12][C:13]2[CH:18]=[CH:17][C:16]([Br:19])=[CH:15][C:14]=2[CH2:20][N:25]2[C@@H:24]([CH3:23])[C@@H:28]([C:29]3[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=3)[O:27][C:26]2=[O:35])[CH:7]=1)[CH3:2]

参加物

3

反応物 2

HCID 8531614-Methyl-5-phenyl-2-oxazolidinone, (4S,5R)-HCID 58237602[3-(4-Bromo-2-bromomethyl-phenoxy)-phenyl]-acetic acid ethyl ester

生成物 1

HCID 58237576{3-[4-Bromo-2-((4S,5R)-4-methyl-2-oxo-5-phenyl-oxazolidin-3-ylmethyl)-phenoxy]-phenyl}-acetic acid ethyl ester

実験手順

Prepared according to the procedure described in Example 6, Step 5, using the following starting materials: [3-(4-Bromo-2-bromomethyl-phenoxy)-phenyl]-acetic acid ethyl ester and (4S,5R)-(−)-4-methyl-5-phenyl-2-oxazolidinone.

後処理

  1. customPrepared

出典と根拠

ORDレコード
ord-b9d6dc1b8cdb47acb15fed27c505dae6
出典データセット
uspto-grants-2012_08
特許番号
US08242145B2

関連ノート

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