2,2-Difluoro-2-phenylethanol → Difluoro-phenyl-acetaldehyde

反応式

[F:1][C:2]([F:11])([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)[CH2:3][OH:4].C1(CCCCOCCC=O)C=CC=CC=1>>[F:1][C:2]([F:11])([C:5]1[CH:6]=[CH:7][CH:8]=[CH:9][CH:10]=1)[CH:3]=[O:4]

参加物

反応物 2

HCID 97938912,2-Difluoro-2-phenylethanol

HCID 866583073-(4-Phenylbutoxy)propionaldehyde

生成物 1

HCID 14644933Difluoro-phenyl-acetaldehyde

実験手順

Obtained from Intermediate 6 (1.0 g, 6.3 mmol) by the procedure described for the Intermediate 13. The title compound was obtained (0.88 g, 86%) as oil.

出典と根拠

ORDレコード: ord-541a4cc110524f05b479b3d3bf17c768
出典データセット: uspto-grants-2012_08
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08242177B2

反応ノート

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