1,1-Dimethoxyethyl(dimethyl)amine → HCID 178464914、化合物

HRID 886044ノート

反応式

HRID 886044 の反応式
[Br:1][C:2]1[CH:18]=[CH:17][C:5]2[C:6]3[N:10]([CH2:11][CH2:12][O:13][C:4]=2[CH:3]=1)[CH:9]=[C:8]([C:14]([NH2:16])=[O:15])[N:7]=3.CO[C:21](OC)([N:23]([CH3:25])[CH3:24])[CH3:22]>C1(C)C=CC=CC=1>[CH3:24][N:23]([CH3:25])/[C:21](=[N:16]/[C:14]([C:8]1[N:7]=[C:6]2[N:10]([CH2:11][CH2:12][O:13][C:4]3[CH:3]=[C:2]([Br:1])[CH:18]=[CH:17][C:5]=32)[CH:9]=1)=[O:15])/[CH3:22]

参加物

4

反応物 2

HCID 878351,1-Dimethoxyethyl(dimethyl)amineHCID 582046299-Bromo-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine-2-carboxamide

生成物 1

HCID 178464914HCID 178464914、化合物

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

反応条件

温度
95 °C

実験手順

To a solution of 8-Bromo-4,5-dihydro-6-oxa-1,3a-diaza-benzo[e]azulene-2-carboxylic acid amide (0.280 g, 0.000909 mol) in toluene (5 mL) was added dimethylacetamide-dimethylacetal (0.405 mL, 0.00273 mol). The solution was stirred at 95° C. for 4 h. The toluene was removed in vacuo to give 8-Bromo-4,5-dihydro-6-oxa-1,3a-diaza-benzo[e]azulene-2-carboxylic acid [1-dimethylamino-eth-(E)-ylidene]-amide. MS (ESI+) 377.1/379.1.

後処理

  1. customThe toluene was removed in vacuo

出典と根拠

ORDレコード
ord-ecddb76815bf44f5a3b9eab28475861d
出典データセット
uspto-grants-2012_08
特許番号
US08242104B2

反応ノート

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