(5-Chloro-2-fluoropyridin-4-yl)boronic acid → (4-((5'-chloro-2'-fluoro-2,4'-bipyridin-6-ylamino)methyl)tetrahydro-2H-pyran-4-yl)methanol

HRID 88618

反応式

[Br:1][c:2]1[cH:3][cH:4][cH:5][c:6]([NH:8][CH2:9][C:10]2([CH2:16][OH:17])[CH2:11][CH2:12][O:13][CH2:14][CH2:15]2)[n:7]1.[Cl:18][c:19]1[c:20]([B:26]([OH:27])[OH:28])[cH:21][c:22]([F:25])[n:23][cH:24]1>>[c:2]1(-[c:20]2[c:19]([Cl:18])[cH:24][n:23][c:22]([F:25])[cH:21]2)[cH:3][cH:4][cH:5][c:6]([NH:8][CH2:9][C:10]2([CH2:16][OH:17])[CH2:11][CH2:12][O:13][CH2:14][CH2:15]2)[n:7]1