Hydrochloric Acid → 4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl 2-oxo-1,2,3,4-tetrahydroquinoline-7-carboxylate hydrochloride
反応式
[O:1]=[C:2]1[CH2:11][CH2:10][C:9]2[C:4](=[CH:5][C:6]([C:12]([O:14][CH2:15][CH2:16][CH2:17][CH2:18][N:19]3[CH2:24][CH2:23][N:22]([C:25]4[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=4[O:31][CH3:32])[CH2:21][CH2:20]3)=[O:13])=[CH:7][CH:8]=2)[NH:3]1.[ClH:33]>>[ClH:33].[O:1]=[C:2]1[CH2:11][CH2:10][C:9]2[C:4](=[CH:5][C:6]([C:12]([O:14][CH2:15][CH2:16][CH2:17][CH2:18][N:19]3[CH2:24][CH2:23][N:22]([C:25]4[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=4[O:31][CH3:32])[CH2:21][CH2:20]3)=[O:13])=[CH:7][CH:8]=2)[NH:3]1参加物
3
実験手順
4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl 2-oxo-1,2,3,4-tetrahydroquinoline-7-carboxylate hydrochloride (24c) (Scheme 4) was prepared from 23c according to the protocol described for the compound 24a (Example 39). The hydrochloride salt 24c gave satisfactory 1H NMR spectral data. Off-white solid, 0.04 g (43%). MS (ESI): m/z=438.2 (M+H+).
出典と根拠
- ORDレコード
- ord-e9b8cb5067624e4584fe6cf59f0f4fad
- 出典データセット
- uspto-grants-2012_08
- 特許番号
- US08247420B2
反応ノート
読み込み中…