Acetic Anhydride → N-(Isoquinolin-3-yl)acetamide
反応式
[NH2:1][C:2]1[N:3]=[CH:4][C:5]2[C:10]([CH:11]=1)=[CH:9][CH:8]=[CH:7][CH:6]=2.[CH3:12][C:13](OC(C)=O)=[O:14]>>[CH:4]1[C:5]2[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=2)[CH:11]=[C:2]([NH:1][C:13](=[O:14])[CH3:12])[N:3]=1参加物
3
実験手順
3-Aminoisoquinoline (495 mg, 3.44 mmol) was stirred in Ac2O (9 mL) at 60° for 16 hours. The mixture was cooled to room temperature and concentrated in vacuo to provide the title compound which was used in the next step without further purification.
後処理
- concentrationconcentrated in vacuo
出典と根拠
- ORDレコード
- ord-fc92afb6bdd2453ab5fb523762a690c5
- 出典データセット
- uspto-grants-2012_08
- 特許番号
- US08247413B2
反応ノート
読み込み中…