3-(4-Aminophenyl)-1,4-dimethylpiperazin-2-one → (R)-5-bromo-3-(4-(1,4-dimethyl-3-oxopiperazin-2-yl)phenylamino)-1-methylpyrazin-2(1H)-one

関与物質

役割	名称	HCID	仕込み量
反応物	3-(4-Aminophenyl)-1,4-dimethylpiperazin-2-one	HCID 57625120	—
反応物	5-Bromo-3-(4-(1,4-dimethyl-3-oxopiperazin-2-yl)phenylamino)-1-methylpyrazin-2(1H)-one	HCID 57625129	—
生成物	(R)-5-bromo-3-(4-(1,4-dimethyl-3-oxopiperazin-2-yl)phenylamino)-1-methylpyrazin-2(1H)-one	HCID 57625140	—

The (R)-isomer of compound 14 can be prepared from the (+)-isomer of 1,4-dimethyl-3-(4-aminophenyl)piperazin-2-one using the same procedure.