alpha-Bromo-o-chlorotoluene → 1-(2-Chlorobenzyl)-2-cyclooctyl-4,4-dimethyl-1,2-diazetidin-3-one

反応式

[CH:1]1([N:9]2[C:12](=[O:13])[C:11]([CH3:15])([CH3:14])[NH:10]2)[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[Cl:16][C:17]1[CH:24]=[CH:23][CH:22]=[CH:21][C:18]=1[CH2:19]Br>>[Cl:16][C:17]1[CH:24]=[CH:23][CH:22]=[CH:21][C:18]=1[CH2:19][N:10]1[C:11]([CH3:15])([CH3:14])[C:12](=[O:13])[N:9]1[CH:1]1[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

参加物

反応物 2

HCID 11905alpha-Bromo-o-chlorotoluene

HCID 673029832-Cyclooctyl-4,4-dimethyl-1,2-diazetidin-3-one

生成物 1

HCID 461956461-(2-Chlorobenzyl)-2-cyclooctyl-4,4-dimethyl-1,2-diazetidin-3-one

実験手順

2-Cyclooctyl-4,4-dimethyl-1,2-diazetidin-3-one and 2-chlorobenzyl bromide were used for a similar reaction and treatment as Process 6 of Example 1, and the title compound was obtained as a colorless oil.

出典と根拠

ORDレコード: ord-24b7f406375b4518a7bfe28649541d31
出典データセット: uspto-grants-2012_08
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08252781B2

反応ノート

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