1-Bromo-5-fluoro-2-methyl-3-nitrobenzene → 4-Bromo-6-fluoro-1H-indole

HRID 888903ノート

反応式

HRID 888903 の反応式
CN(C)S([C:6]1[CH:14]=[C:13]2[C:9]([CH:10]=[CH:11][NH:12]2)=[C:8]([Br:15])[CH:7]=1)(=O)=O.BrC1C=C([F:24])C=C([N+]([O-])=O)C=1C>>[Br:15][C:8]1[CH:7]=[C:6]([F:24])[CH:14]=[C:13]2[C:9]=1[CH:10]=[CH:11][NH:12]2

参加物

3

反応物 2

HCID 27733851-Bromo-5-fluoro-2-methyl-3-nitrobenzeneHCID 591513424-bromo-1H-indole-6-sulfonic acid dimethylamide

生成物 1

HCID 247281734-Bromo-6-fluoro-1H-indole

実験手順

Prepared according to the method used in the preparation of 4-bromo-1H-indole-6-sulfonic acid dimethylamide using 1-bromo-5-fluoro-2-methyl-3-nitro-benzene in place of 3-bromo-4-N,N-trimethyl-5-nitro-benzenesulfonamide. The title compound was obtained as a white solid (6.06 g, 33%).

後処理

  1. customPrepared

出典と根拠

ORDレコード
ord-39a1186c9dde4a19b56ccaa3fe1d81a5
出典データセット
uspto-grants-2012_08
特許番号
US08252792B2

反応ノート

読み込み中…