化工社化工社 化学情報印刷レポート · 研究参考用
Iodine → 2-cyclopropyl-5-iodo-1H-imidazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Iodine | HCID 807 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | Sodium Sulfite | HCID 24437 | — |
| 反応物 | 2-cyclopropyl-1H-imidazole | HCID 17942383 | — |
| 反応物 | 2-Cyclopropyl-4,5-diiodo-1h-imidazole | HCID 21985395 | — |
| 生成物 | 2-cyclopropyl-5-iodo-1H-imidazole | HCID 21985392 | — |
反応手順
The title compound was prepared in accordance with the literature reference of Cliff & Pyne, Synthesis-Stuttgart (7), 681–682(1994) by reacting 2-cyclopropyl-1H-imidazole with iodine in the presence of NaOH. The obtained 4,5-diiodo-2-cyclopropyl-1H-imidazole was then reacted with sodium sulfite to obtain the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07091222B2 |
| 出典データセット | uspto-grants-2006_08 |
| ORD ID | ord-4a51539e54e6499c8098a02ac20b71d4 |
| 出典メモ | uspto-grants-2006_08 |