関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Acetic Acid | HCID 176 | — |
| 反応物 | DL-alanine | HCID 602 | — |
| 反応物 | Acetic Anhydride | HCID 7918 | — |
| 溶媒 | Ethyl Acetate | HCID 8857 | — |
| 生成物 | N-Acetyl-L-alanine | HCID 88064 | — |
反応手順
134 g (1.50 mol) of DL-alanine are introduced into acetic acid and treated dropwise with 230 g (2.25 mol) of acetic anhydride. The mixture is additionally stirred at 100° C. for 2 h to complete the reaction and the solvent is then stripped off in vacuo. The solid obtained is suspended in ethyl acetate and filtered off with suction. For purification, the solid is washed several times with diethyl ether.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US06998402B2 |
|---|
| 出典データセット | uspto-grants-2006_02 |
|---|
| ORD ID | ord-7a7506be6c624ae69389ab1b1fb4279d |
|---|
| 出典メモ | uspto-grants-2006_02 |
|---|
