化工社化工社 化学情報印刷レポート · 研究参考用
6-Methyl-2-nitrobenzoic acid → Methyl 2-methyl-6-nitrobenzoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 6-Methyl-2-nitrobenzoic acid | HCID 16097 | — |
| 反応物 | Trimethylsilyldiazomethane | HCID 167693 | — |
| 生成物 | Methyl 2-methyl-6-nitrobenzoate | HCID 596057 | — |
反応手順
2-Methyl-6-nitrobenzoic acid is reacted with trimethylsilyldiazomethane to yield methyl 2-methyl-6-nitrobenzoate with m.p. 44–45° (Chem. Pharm. Bull., Vol. 29, 1475 (1981)). Methyl 2-methyl-6-nitrobenzoate is hydrogenated in methanol in the presence of palladium, 10% on carbon powder, at room temperature and atmospheric pressure to give methyl 2-methyl-6-aminobenzoate.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07002022B2 |
| 出典データセット | uspto-grants-2006_02 |
| ORD ID | ord-c427f61a2cc74ca7982072224fa336e4 |
| 出典メモ | uspto-grants-2006_02 |