Aluminum bromide → 4-(4-fluorophenoxy)-5-[4-(methylsulfonyl)phenyl]-3(2H)-pyridazinone

HRID 891304

反応式

HRID 891304 の反応式
C([N:8]1[C:13](=[O:14])[C:12]([O:15][C:16]2[CH:21]=[CH:20][C:19]([F:22])=[CH:18][CH:17]=2)=[C:11]([C:23]2[CH:28]=[CH:27][C:26]([S:29]([CH3:32])(=[O:31])=[O:30])=[CH:25][CH:24]=2)[CH:10]=[N:9]1)C1C=CC=CC=1.[Al](Br)(Br)Br>C1(C)C=CC=CC=1>[F:22][C:19]1[CH:18]=[CH:17][C:16]([O:15][C:12]2[C:13](=[O:14])[NH:8][N:9]=[CH:10][C:11]=2[C:23]2[CH:24]=[CH:25][C:26]([S:29]([CH3:32])(=[O:31])=[O:30])=[CH:27][CH:28]=2)=[CH:21][CH:20]=1

参加物

4

反応物 2

HCID 24409Aluminum bromideHCID 98465812-Benzyl-4-(4-fluorophenoxy)-5-[4-(methylsulfonyl)phenyl]-3(2H)-pyridazinone

生成物 1

HCID 219341624-(4-fluorophenoxy)-5-[4-(methylsulfonyl)phenyl]-3(2H)-pyridazinone

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

The title compound was prepared by treating 2-benzyl-4-(4-fluorophenoxy)-5-[4-(methylsulfonyl)phenyl]-3(2H)-pyridazinone (Example 75) with AlBr3 in toluene according to the procedure in Example 11 (yield: 1.8 g, 95%).

出典と根拠

ORDレコード
ord-e87118ab7853444f87dda44a2479da3a
出典データセット
uspto-grants-2006_02
特許番号
US07001895B2

関連ノート

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