化工社化工社 化学情報印刷レポート · 研究参考用
5-(4-Chlorophenyl)-2-furoic acid → (R)-N-(1-Azabicyclo[2.2.2]oct-3-yl)(5-(4-chlorophenyl)furan-2-carboxamide)
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 5-(4-Chlorophenyl)-2-furoic acid | HCID 726693 | — |
| 反応物 | (R)-(+)-3-Aminoquinuclidine Dihydrochloride | HCID 12494972 | — |
| 生成物 | (R)-N-(1-Azabicyclo[2.2.2]oct-3-yl)(5-(4-chlorophenyl)furan-2-carboxamide) | HCID 23599454 | — |
反応手順
Prepared by a method analogous to that described in Example 1 from (R)-1-azabicyclo[2.2.2]oct-3-ylamine dihydrochloride and 5-(4-chlorophenyl)furoic acid; the compound was purified by chromatography on silica gel using ammoniated methanol/chloroform mixtures as the eluent; MS (ES+) 331, 333 (MH+).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07001914B2 |
| 出典データセット | uspto-grants-2006_02 |
| ORD ID | ord-b26baa301631403db5127f963bca7e20 |
| 出典メモ | uspto-grants-2006_02 |