Acetic Anhydride → HCID 578922、化合物

反応式

[CH3:1][C:2]1[CH:3]=[C:4]([OH:9])[CH:5]=[C:6]([CH3:8])[CH:7]=1.[C:10](OC(=O)C)(=[O:12])[CH3:11]>>[C:10]([O:9][C:4]1[CH:5]=[C:6]([CH3:8])[CH:7]=[C:2]([CH3:1])[CH:3]=1)(=[O:12])[CH3:11]

参加物

反応物 2

HCID 7918Acetic Anhydride

HCID 79483,5-Dimethylphenol

生成物 1

HCID 578922HCID 578922、化合物収率 103.1%

実験手順

206.5 g (1.69 mol) of 3,5-dimethylphenol and 337.3 g (3.30 mol) of acetic anhydride were refluxed for 1 h and then stirred at RT overnight. The mixture was poured onto water and extracted with methylene chloride. The organic phase was washed with sodium hydroxide solution and water, dried and concentrated under reduced pres-sure. 286 g of 3,5-dimethylphenyl acetate were obtained.

後処理

additionThe mixture was poured onto water
extractionextracted with methylene chloride
washThe organic phase was washed with sodium hydroxide solution and water
customdried
concentrationconcentrated under reduced pres-sure

出典と根拠

ORDレコード: ord-a5468a53ca4044608cfedb822269f63a
出典データセット: uspto-grants-1992_06
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05118682

反応ノート

読み込み中…

参加物