Bromine → HCID 15005405、化合物
反応式
[Br:1]Br.[O:3]=[C:4]([CH3:14])[CH2:5][C:6]1[CH:13]=[CH:12][C:9]([C:10]#[N:11])=[CH:8][CH:7]=1>ClCCl>[Br:1][CH:5]([C:6]1[CH:13]=[CH:12][C:9]([C:10]#[N:11])=[CH:8][CH:7]=1)[C:4](=[O:3])[CH3:14]参加物
4
実験手順
Bromine (5.28 g) in dichloromethane (80 ml) was added dropwise at 25° C. over 1 hour to 4-(2-oxopropyl)benzonitrile in dichloromethane (85 ml). The reaction mixture was stirred for 1/2 hour after the addition was complete. The mixture was washed with brine (50 ml), dried over magnesium sulphate and the solvent removed under reduced pressure to yield the title compound as a pale red oil (7.55 g, 96%).
後処理
- additionafter the addition
- washThe mixture was washed with brine (50 ml)
- dry with materialdried over magnesium sulphate
- customthe solvent removed under reduced pressure
出典と根拠
- ORDレコード
- ord-ee3ef274294740f08d1c883d4715c28d
- 出典データセット
- uspto-grants-1992_06
- 特許番号
- US05120747
反応ノート
読み込み中…