Einecs 211-027-4 → 2,4-Dihydroxybenzonitrile

HRID 893028

反応式

HRID 893028 の反応式
C[O:2][C:3]1[CH:10]=[C:9]([O:11]C)[CH:8]=[CH:7][C:4]=1[C:5]#[N:6].[Cl-].[NH+]1C=CC=CC=1>O>[OH:2][C:3]1[CH:10]=[C:9]([OH:11])[CH:8]=[CH:7][C:4]=1[C:5]#[N:6]

参加物

4

反応物 2

HCID 69401Einecs 211-027-4HCID 777502,4-Dimethoxybenzonitrile

生成物 1

HCID 30175202,4-Dihydroxybenzonitrile収率 70.6%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

2,4-dimethoxybenzonitrile (2 g) was mixed with pyridinium chloride (5.67 g) and the reaction mixture was fused at 210° C. for 2 hours. After being left to stand at room temperature overnight, the mixture was diluted with water and extracted into diethyl ether. The ether extracts were washed with water, dried over magnesium sulphate and concentrated to give a pink solid which was washed with petrol and air dried to give 2,4-dihydroxybenzonitrile (1.17 g) (m pt 176°-178° C.).

後処理

  1. waitAfter being left
  2. waitto stand at room temperature overnight
  3. extractionextracted into diethyl ether
  4. washThe ether extracts were washed with water
  5. dry with materialdried over magnesium sulphate
  6. concentrationconcentrated
  7. customto give a pink solid which
  8. washwas washed with petrol and air
  9. customdried

出典と根拠

ORDレコード
ord-36be83b118b94df19f3b2a5413ac103c
出典データセット
uspto-grants-1992_06
特許番号
US05120869

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