Urea → N-Butyl-N'-propan-2-ylurea

反応式

[CH:1]([NH:4][C:5]([NH2:7])=[O:6])([CH3:3])[CH3:2].NC(N)=O.[CH2:12](Br)[CH2:13][CH2:14][CH3:15]>>[CH2:12]([NH:7][C:5]([NH:4][CH:1]([CH3:3])[CH3:2])=[O:6])[CH2:13][CH2:14][CH3:15]

参加物

反応物 3

HCID 1176Urea

HCID 8002Butyl bromide

HCID 12725Isopropylurea

生成物 1

HCID 14984935N-Butyl-N'-propan-2-ylurea収率 58%

実験手順

N-butyl-N'-isopropylurea was prepared in a yield of 58% as described in Example 1, but using 2.04 g of N-isopropylurea (20 mmol) as the urea and 2.74 g of butylbromide (20 mmol) as the alkylating agent.

出典と根拠

ORDレコード: ord-c4ad44d3e6604ce99aed7677f98915c1
出典データセット: uspto-grants-1992_06
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05124451

反応ノート

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