Ammonium Chloride → HCID 15341843、化合物

反応式

[CH:1]1([CH2:4][C:5]2[C:6]([OH:16])=[C:7]([CH:12]=[CH:13][C:14]=2[OH:15])[C:8](OC)=[O:9])[CH2:3][CH2:2]1.[Cl-].[NH4+:18]>>[CH:1]1([CH2:4][C:5]2[C:6]([OH:16])=[C:7]([CH:12]=[CH:13][C:14]=2[OH:15])[C:8]([NH2:18])=[O:9])[CH2:3][CH2:2]1

参加物

反応物 2

HCID 25517Ammonium Chloride

HCID 15341799HCID 15341799、化合物

生成物 1

HCID 15341843HCID 15341843、化合物

実験手順

The compound of Example 15 is heated at 50° C. in a saturated ammonium chloride solution overnight. The reaction mixture is thoroughly extracted with ethyl acetate, and the solvent dried (Na2SO4) and evaporated in vacuo to afford the crude product. Chromatographic purification or silica gel using ethyl acetate/hexane (4:6) as eluant affords the product.

後処理

extractionThe reaction mixture is thoroughly extracted with ethyl acetate
dry with materialthe solvent dried (Na2SO4)
customevaporated in vacuo

出典と根拠

ORDレコード: ord-71a48cbf662e413eadfd439cf6f36b22
出典データセット: uspto-grants-1992_06
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05124350

反応ノート

読み込み中…

参加物