Water → HCID 18793861、化合物

HRID 893937ノート

反応式

HRID 893937 の反応式
[CH2:1]([O:3][C:4](=[O:11])[CH2:5][C:6]1[N:7]=[CH:8][S:9][CH:10]=1)[CH3:2].[OH2:12]>ClCCCl>[CH2:1]([O:3][C:4](=[O:11])[C:5]([C:6]1[N:7]=[CH:8][S:9][CH:10]=1)=[O:12])[CH3:2]

参加物

4

反応物 2

HCID 962WaterHCID 4737345Ethyl 2-(1,3-thiazol-4-yl)acetate

生成物 1

HCID 18793861HCID 18793861、化合物

試薬・触媒・溶媒 1

HCID 111,2-Dichloroethane溶媒

実験手順

Alternatively, the 1,3-thiazol-4-yl-glyoxyl ester is obtained by heating 17.1 g of 1,3-thiazol-4-yl-acetic acid ethyl ester in 50 ml of 1,2-dichloroethane together with 10.5 g of SeO2 with reflux on a water separator. When the separation of water is complete, the mixture is filtered with suction, the residue is washed with 1,2-dichloroethane, the combined dichloroethane phases are concentrated and the residue is distilled.

後処理

  1. customWhen the separation of water
  2. filtrationthe mixture is filtered with suction
  3. washthe residue is washed with 1,2-dichloroethane
  4. concentrationthe combined dichloroethane phases are concentrated
  5. distillationthe residue is distilled

出典と根拠

ORDレコード
ord-b9582bed11d04d15ab86b729fd7e044e
出典データセット
uspto-grants-1981_08
特許番号
US04282220

反応ノート

読み込み中…