Hydrochloric Acid → 2-Ethyl-3-(3-mercapto-2-methylpropanoyl)-4-thiazolidinecarboxylic acid
反応式
C([S:4][CH2:5][CH:6]([CH3:19])[C:7]([N:9]1[CH:13]([C:14]([OH:16])=[O:15])[CH2:12][S:11][CH:10]1[CH2:17][CH3:18])=[O:8])(=O)C.Cl>O.N>[CH2:17]([CH:10]1[N:9]([C:7](=[O:8])[CH:6]([CH3:19])[CH2:5][SH:4])[CH:13]([C:14]([OH:16])=[O:15])[CH2:12][S:11]1)[CH3:18]参加物
5
実験手順
3-(3-Acetylthio-2-methylpropanoyl)-2-ethyl-4-thiazolidinecarboxylic acid (1 g.) is dissolved in a mixture of water (3 ml.) and concentrated ammonia (3 ml.) under a blanket of argon. The mixture is stirred at room temperature for thirty minutes and acidified with concentrated hydrochloric acid. The organic layer is dried and concentrated to dryness in vacuo to yield 2-ethyl-3-(3-mercapto-2-methylpropanoyl)-4-thiazolidinecarboxylic acid.
後処理
- customThe organic layer is dried
- concentrationconcentrated to dryness in vacuo
出典と根拠
- ORDレコード
- ord-1d78955449c64d8db336bb233f9b684d
- 出典データセット
- uspto-grants-1981_08
- 特許番号
- US04282235
反応ノート
読み込み中…