Trifluoroacetic anhydride → 2-Bromo-6H-dibenz[b,e]oxepin-11-one
反応式
[Br:1][C:2]1[CH:18]=[CH:17][C:5]([O:6][CH2:7][C:8]2[CH:16]=[CH:15][CH:14]=[CH:13][C:9]=2[C:10]([OH:12])=O)=[CH:4][CH:3]=1.FC(F)(F)C(OC(=O)C(F)(F)F)=O>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[O:6][CH2:7][C:8]3[CH:16]=[CH:15][CH:14]=[CH:13][C:9]=3[C:10](=[O:12])[C:17]=2[CH:18]=1参加物
3
実験手順
Reflux 120 gm. of o-(p-bromophenoxymethyl)benzoic acid in 500 cc. of trifluoroacetic anhydride containing 0.5 cc. of boron trifluoride-ether complex for 31/2 hours. Cool, separate the solids by filtration, and wash with ether in order to obtain the title product (m.p. 136°-139° C.).
後処理
- temperatureReflux 120 gm
- custom2 hours
- temperatureCool
- customseparate the solids
- filtrationby filtration
- washwash with ether in order
出典と根拠
- ORDレコード
- ord-8f99849fe0cf4d9cbff1d35a73ed03e0
- 出典データセット
- uspto-grants-1981_08
- 特許番号
- US04282365
反応ノート
読み込み中…