5-bromo-N-(3-pyridinylmethyl)-2-thiophenesulfonamide → 5-[7-Difluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-thiophene-2-sulfonic acid (pyridin-3-ylmethyl)-amide

HRID 89419ノート

反応式

HRID 89419 の反応式
[F:1][CH:2]([c:3]1[cH:4][c:5](-[c:14]2[cH:15][cH:16][c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][cH:19]2)[n:6][c:7]2[n:8]1[n:9][cH:10][c:11]2[C:12]#[CH:13])[F:24].[n:25]1[cH:26][c:27]([CH2:31][NH:32][S:33](=[O:34])(=[O:35])[c:36]2[s:37][c:38]([Br:41])[cH:39][cH:40]2)[cH:28][cH:29][cH:30]1>>[F:1][CH:2]([c:3]1[cH:4][c:5](-[c:14]2[cH:15][cH:16][c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][cH:19]2)[n:6][c:7]2[n:8]1[n:9][cH:10][c:11]2[C:12]#[C:13][c:38]1[s:37][c:36]([S:33]([NH:32][CH2:31][c:27]2[cH:26][n:25][cH:30][cH:29][cH:28]2)(=[O:34])=[O:35])[cH:40][cH:39]1)[F:24]

参加物

3

反応物 2

HCID 6626665-bromo-N-(3-pyridinylmethyl)-2-thiophenesulfonamideHCID 866080343-Ethynyl-7-difluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine

生成物 1

HCID 670003435-[7-Difluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-thiophene-2-sulfonic acid (pyridin-3-ylmethyl)-amide

出典と根拠

ORDレコード
ord-b6c0e2fe10f84ee88cf2951f2dbcb258
出典データセット
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

反応ノート

読み込み中…