1,2-Dichloroethane → 4,5-Dichloro-2-(4-chlorophenoxy)anisole

HRID 894903

反応式

HRID 894903 の反応式
[Cl:1]Cl.[O:3]([C:10]1[CH:15]=CC=[CH:12][C:11]=1[O:16][CH3:17])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[Cl:18][CH2:19][CH2:20][Cl:21]>>[Cl:18][C:19]1[C:20]([Cl:21])=[CH:12][C:11]([O:16][CH3:17])=[C:10]([O:3][C:4]2[CH:9]=[CH:8][C:7]([Cl:1])=[CH:6][CH:5]=2)[CH:15]=1

参加物

4

反応物 3

HCID 111,2-DichloroethaneHCID 24526ChlorineHCID 2487582-Methoxyphenyl phenyl ether

生成物 1

HCID 205749064,5-Dichloro-2-(4-chlorophenoxy)anisole

実験手順

With stirring, 11.5 g of chlorine are introduced at room temperature into a solution of 8 g of 2-phenoxyanisole in 85 ml of 1,2-dichloroethane in the course of 20 minutes. The reaction mixture is then stirred for 30 minutes at room temperature. The solvent is removed by evaporation and the crystalline residue is recrystallised from methanol, affording 4,5-dichloro-2-(4-chlorophenoxy)anisole in the form of white crystals with a melting point of 105°-106° C.

後処理

  1. stirringThe reaction mixture is then stirred for 30 minutes at room temperature
  2. customThe solvent is removed by evaporation
  3. customthe crystalline residue is recrystallised from methanol

出典と根拠

ORDレコード
ord-88182dad8232413f987ba9bd5162f0e6
出典データセット
uspto-grants-1981_08
特許番号
US04284828

関連ノート

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