Hydrochloric Acid → 1-[3-(3-ethoxy-4-methoxyphenyl)-5,6-dihydro-4H-pyridazin-1-yl]-1-(4-methyl-2-pyridin-2-ylthiazol-5-yl)methanone

反応式

[CH2:1]([CH3:2])[O:3][c:4]1[cH:5][c:6]([C:12]2=[N:13][NH:14][CH2:15][CH2:16][CH2:17]2)[cH:7][cH:8][c:9]1[O:10][CH3:11].[CH3:18][c:19]1[n:20][c:21](-[c:27]2[n:28][cH:29][cH:30][cH:31][cH:32]2)[s:22][c:23]1[C:24](=[O:25])[Cl:26].[ClH:33]>>[CH2:1]([CH3:2])[O:3][c:4]1[cH:5][c:6]([C:12]2=[N:13][N:14]([C:24]([c:23]3[c:19]([CH3:18])[n:20][c:21](-[c:27]4[n:28][cH:29][cH:30][cH:31][cH:32]4)[s:22]3)=[O:25])[CH2:15][CH2:16][CH2:17]2)[cH:7][cH:8][c:9]1[O:10][CH3:11]

参加物

反応物 3

HCID 313Hydrochloric Acid

HCID 115938543-(3-ethoxy-4-methoxyphenyl)-5,6-dihydro4H-pyridazine

HCID 772302994-Methyl-2-pyridin-2-yl-1,3-thiazole-5-carbonyl chloride

生成物 1

HCID 104781841-[3-(3-ethoxy-4-methoxyphenyl)-5,6-dihydro-4H-pyridazin-1-yl]-1-(4-methyl-2-pyridin-2-ylthiazol-5-yl)methanone

出典と根拠

ORDレコード: ord-565919d9c1f14e4f82e1856493310d8e
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…