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HRID 895091作成日:2026年10月25日

Formaldehyde → L-Pantothenic acid

https://huagongshe.com/reaction/895091

反応式

関与物質

役割名称HCID仕込み量
反応物FormaldehydeHCID 712—
反応物(+-)-PantolactoneHCID 989—
反応物CyanideHCID 5975—
反応物Pantothenic AcidHCID 6613—
生成物L-Pantothenic acidHCID 5748353—

反応手順

Pantothenic acid can be prepared by chemical synthesis, or biotechnologically by fermentation of suitable microorganisms in suitable nutrient solutions. In the chemical synthesis, DL-pantolactone is an important precursor. It is prepared in a multi-stage process from formaldehyde, isobutylaldehyde and cyanide, and in further process steps, the racemic mixture is separated, D-pantolactone is subjected to a condensation reaction with β-alanine, and D-pantothenic acid is obtained in this way.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US06913912B2
出典データセットuspto-grants-2005_07
ORD IDord-704c341d0813481cb1f59574402cd31a
出典メモuspto-grants-2005_07