Diethanolamine → 4-[[Bis(2-hydroxyethyl)amino]methyl]-2,6-ditert-butylphenol

HRID 895833

反応式

HRID 895833 の反応式
[C:1]([C:5]1[CH:6]=[C:7]([CH:10]=[C:11]([C:14]([CH3:17])([CH3:16])[CH3:15])[C:12]=1[OH:13])[CH2:8]Br)([CH3:4])([CH3:3])[CH3:2].[CH2:18]([NH:21][CH2:22][CH2:23][OH:24])[CH2:19][OH:20]>C1C=CC=CC=1>[C:1]([C:5]1[CH:6]=[C:7]([CH2:8][N:21]([CH2:22][CH2:23][OH:24])[CH2:18][CH2:19][OH:20])[CH:10]=[C:11]([C:14]([CH3:17])([CH3:16])[CH3:15])[C:12]=1[OH:13])([CH3:4])([CH3:3])[CH3:2]

参加物

4

反応物 2

HCID 8113DiethanolamineHCID 612973Phenol, 4-(bromomethyl)-2,6-bis(1,1-dimethylethyl)-

生成物 1

HCID 6129064-[[Bis(2-hydroxyethyl)amino]methyl]-2,6-ditert-butylphenol

試薬・触媒・溶媒 1

HCID 241Benzene溶媒

反応条件

温度
77.5 °C

実験手順

In a round bottom flask taken 2.24 gm of 3,5-ditertbutyl-4-hydroxy benzyl bromide and 0.6 ml of N, N-diethanol amine and dissolved in 100 mL of benzene. The reaction mixture was refluxed with constant stirring at 75-80° C. for 6 hrs. The product was crystallized out in the form of colorless needles. The solvent was decanted, crystals were filtered off and washed with pure benzene. The yield of the product is 1.43 gm (64%). Product was identified by 1H-NMR and FT-IR spectroscopic techniques.

後処理

  1. customIn a round bottom flask taken
  2. temperatureThe reaction mixture was refluxed
  3. customThe product was crystallized out in the form of colorless needles
  4. customThe solvent was decanted
  5. filtrationcrystals were filtered off
  6. washwashed with pure benzene

出典と根拠

ORDレコード
ord-662132d85dd44539b71e41dcfab17a69
出典データセット
uspto-grants-2005_07
特許番号
US06916960B2

関連ノート

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