1H-indol-4-ol → 3-(Dimethylaminophenylmethyl)-1H-indol-4-ol

反応式

[OH:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH:4]=[CH:5][NH:6]2.[Cl-].[CH:12](=[N+:19]([CH3:21])[CH3:20])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[CH3:20][N:19]([CH:12]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[C:4]1[C:3]2[C:2]([OH:1])=[CH:10][CH:9]=[CH:8][C:7]=2[NH:6][CH:5]=1)[CH3:21]

参加物

反応物 2

HCID 754211H-indol-4-ol

HCID 11073839Methanaminium, N-methyl-N-(phenylmethylene)-, chloride

生成物 1

HCID 98784763-(Dimethylaminophenylmethyl)-1H-indol-4-ol

実験手順

The preparation was carried out in accordance with general synthesis instructions 4 from 4-hydroxy-1H-indole and benzylidene-dimethyl-ammonium chloride, which had been prepared in accordance with example 1.

後処理

customhad been prepared in accordance with example 1

出典と根拠

ORDレコード: ord-0be84a70ba3545d5b8875c78bac9b1ac
出典データセット: uspto-grants-2006_08
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07091220B2

反応ノート

読み込み中…