化工社化工社 化学情報印刷レポート · 研究参考用
Trifluoroacetic acid → (4-{2-[2-(Methoxycarbonyl)phenoxy]ethyl}phenoxy)acetic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Trifluoroacetic acid | HCID 6422 | — |
| 反応物 | Methyl 2-{2-[4-(2-tert-butoxy-2-oxoethoxy)phenyl]ethoxy}benzoate | HCID 69259306 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | (4-{2-[2-(Methoxycarbonyl)phenoxy]ethyl}phenoxy)acetic acid | HCID 69258392 | 95% |
反応手順
Methyl 2-{2-[4-(2-tert-butoxy-2-oxoethoxy)phenyl]ethoxy}benzoate (0.400 g, 1.0351 mmol) was dissolved in DCM and trifluoracetic acid (0.8 ml, 8.281 mmol) was added. The mixture was stirred at room temperature for 3 h. The solvent was evaporated to give 325 mg of a white powder.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07351858B2 |
| 出典データセット | uspto-grants-2008_04 |
| ORD ID | ord-03c3e0039056428a82fe06c4ce0e4358 |
| 出典メモ | uspto-grants-2008_04 |