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4-Aminophenol → 4-(2-(N-isopropylcarbamoyl)-4-pyridyloxy)aniline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Aminophenol | HCID 403 | — |
| 反応物 | Isopropylamine | HCID 6363 | — |
| 反応物 | 4-chloropyridine-2-carbonyl Chloride | HCID 11095146 | — |
| 反応物 | 4-Chloro-N-isopropyl-pyridine-2-carboxamide | HCID 22832083 | — |
| 生成物 | 4-(2-(N-isopropylcarbamoyl)-4-pyridyloxy)aniline | HCID 23614560 | — |
反応手順
Entry 66: 4-Chloropyridine-2-carbonyl chloride was reacted with isopropylamine according to Method A2, Step 3b. The resulting 4-chloro-N-isopropyl-2-pyridinecarboxamide was reacted with 4-aminophenol according to Method A2, Step 4 to give 4-(2-(N-isopropylcarbamoyl)-4-pyridyloxy)aniline. According to Method C1a, 4-chloro-3-(trifluoromethyl)phenyl isocyanate was reacted with 4-(2-(N-isopropylcarbamoyl)-4-pyridyloxy)aniline to afford the urea.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07351834B1 |
| 出典データセット | uspto-grants-2008_04 |
| ORD ID | ord-210f369667044b38b92549347f224445 |
| 出典メモ | uspto-grants-2008_04 |