Thiophosgene → HCID 178424321、化合物

HRID 900267

反応式

HRID 900267 の反応式
N[C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:12](=[O:13])[C:11]3[CH:14]=[C:15]([Cl:18])[CH:16]=[CH:17][C:10]=3[C:9]2=[O:19])=[C:4]([CH3:20])[CH:3]=1.C(Cl)(Cl)=[S:22]>CC(C)=O>[N-:8]=[C:12]=[S:22].[Cl:18][C:15]1[CH:16]=[CH:17][C:10]2[C:9](=[O:19])[N:8]([C:5]3[CH:6]=[CH:7][CH:2]=[CH:3][C:4]=3[CH3:20])[C:12](=[O:13])[C:11]=2[CH:14]=1

参加物

4

反応物 2

HCID 10040ThiophosgeneHCID 93991N-(4-Amino-o-tolyl)-4-chlorophthalimide

生成物 1

HCID 178424321HCID 178424321、化合物収率 148.1%

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

To a slurry of 150 mg (0.52 mmol) of 2-(4-amino-2-methylphenyl)-5-chlorobenzo[c]azoline-1,3-dione in 2 mL of acetone, was added 41 uL (0.54 mmol) of thiophosgene. The yellow slurry dissolved whereupon a white precipitate formed. After 1 h, this solid was collected by filtration and dried to give 127 mg (74%) of the desired product.

後処理

  1. dissolutionThe yellow slurry dissolved whereupon a white precipitate
  2. customformed
  3. filtrationthis solid was collected by filtration
  4. customdried

出典と根拠

ORDレコード
ord-1ef5c50be5d14271b49b2761d53ac2e8
出典データセット
uspto-grants-2008_04
特許番号
US07358257B2

関連ノート

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