[Al+3].[Cl-].[Cl-].[Cl-].[C:5](Cl)(=[O:7])[CH3:6].[CH3:9][O:10][C:11]1[CH:12]=[C:13]2[C:17](=[CH:18][CH:19]=1)[CH:16]([CH:20]([CH2:25][CH3:26])[C:21]([O:23][CH3:24])=[O:22])[CH2:15][CH2:14]2>C(Cl)Cl>[C:5]([C:19]1[CH:18]=[C:17]2[C:13]([CH2:14][CH2:15][CH:16]2[CH:20]([CH2:25][CH3:26])[C:21]([O:23][CH3:24])=[O:22])=[CH:12][C:11]=1[O:10][CH3:9])(=[O:7])[CH3:6]To a solution of AlCl3 (103 mg, 0.78 mmol) in methylene chloride (2.5 mL) at 0° C., was added acetyl chloride (0.044 mL, 0.63 mmol), followed by the addition of a solution of methyl 5-methoxy-2,3-dihydro-1H-indene-1-yl-butanoate (130 mg, 0.52 mmol) in methylene chloride (2.7 mL) dropwise. The mixture was stirred at 0° C. for 15 minutes. The ice bath was removed and the mixture stirred at rt for 16 hours. The mixture was poured over ice and 4 drops of conc. HCl were added. This mixture was extracted with methylene chloride twice. The combined organic layers were washed with water, 0.05 N NaOH and water. The organic layer was dried, concentrated, and purified by chromatography with 10% EtOAc:hexane to give desired product (103 mg, 68%). Rf=0.28 (4:1 hexane:EtOAc); GC-MS (+Cl): m/z=291 (M+); 1H NMR (DMSO-d6): δ 0.840 (m, 3H), 1.536 (m, 2H), 1.876 (m, 1H), 2.108 (m, 1H), 2.505 (s, 3H), 2.521 (m, 1H), 2.760-2.889 (m, 2H), 3.236 (m, 1H), 3.511 and 3.589 (s, 3H), 3.836 (s, 3H), 7.012 and 7.253 (s, 1H), 7.440 (s, 1H).
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