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HRID 900561作成日：2026年10月26日

3,5-Dichloro-4-hydroxybenzoic acid → 3-({1-[2-(3,5-Dichloro-4-hydroxybenzoylamino)-3-methanesulfonyl-propionyl]-pyrrolidine-2-carbonyl}-amino)-4-oxo-butyric Acid

https://huagongshe.com/reaction/900561

反応式

関与物質

役割名称HCID仕込み量
反応物3,5-Dichloro-4-hydroxybenzoic acidHCID 18749—
反応物3-({1-[2-(4-Amino-3-chloro-benzoylamino)-3-methylsulfonyl-propionyl]-pyrrolidine-2-carbonyl}-amino)-4-oxo-butyric acidHCID 18623771—
生成物3-({1-[2-(3,5-Dichloro-4-hydroxybenzoylamino)-3-methanesulfonyl-propionyl]-pyrrolidine-2-carbonyl}-amino)-4-oxo-butyric AcidHCID 18623770—

反応手順

Compound 20s was prepared according to the procedure used for the preparation of 20i, using 3,5-dichloro-4-hydroxybenzoic acid in place of 1-isoquinolinecarboxylic acid.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07358273B2
出典データセットuspto-grants-2008_04
ORD IDord-5e08b25201134761ab3b9297ce971fa1
出典メモuspto-grants-2008_04