2-Phenylindole → 3-[(2-Chlorophenyl)-piperidin-1-yl-methyl]-2-phenyl-1H-indole

HRID 9011

反応式

HRID 9011 の反応式
[C:1]1([C:7]2[NH:8][C:9]3[C:14]([CH:15]=2)=[CH:13][CH:12]=[CH:11][CH:10]=3)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Cl-].[Cl:17][C:18]1[CH:30]=[CH:29][CH:28]=[CH:27][C:19]=1[CH:20]=[N+:21]1[CH2:26][CH2:25][CH2:24][CH2:23][CH2:22]1>>[Cl:17][C:18]1[CH:30]=[CH:29][CH:28]=[CH:27][C:19]=1[CH:20]([N:21]1[CH2:26][CH2:25][CH2:24][CH2:23][CH2:22]1)[C:15]1[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[NH:8][C:7]=1[C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

参加物

3

反応物 2

HCID 136982-PhenylindoleHCID 179587471-(2-Chloro-benzylidene)-piperidinium chloride

生成物 1

HCID 102723573-[(2-Chlorophenyl)-piperidin-1-yl-methyl]-2-phenyl-1H-indole

実験手順

The preparation was carried out in accordance with general synthesis instructions 4 from 2-phenyl-1H-indole and 1-(2-chloro-benzylidene)-piperidinium chloride, which had been prepared in accordance with example 26.

後処理

  1. customhad been prepared in accordance with example 26

出典と根拠

ORDレコード
ord-e753da79418a45e58eb565e7c3d4e2a9
出典データセット
uspto-grants-2006_08
特許番号
US07091220B2

関連ノート

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