関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Ethyl formate | HCID 8025 | — |
| 反応物 | 5-Aminopentan-1-ol | HCID 75634 | — |
| 生成物 | 5-Hydroxypentylformamide | HCID 19782300 | 73% |
反応手順
2.06 g (20.0 mmol) of 5-amino-1-pentanol was dissolved in 5 mL of ethyl formate and the mixture was stirred at 90° C. for 4 hours. The solvent was distilled off under reduced pressure and the obtained residue was purified by silica gel chromatography (eluting solvent: ethyl acetate/methanol=100/0-70/30) to obtain 1.90 g (yield: 73%) of the title compound as a pale yellow-oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07365067B2 |
|---|
| 出典データセット | uspto-grants-2008_04 |
|---|
| ORD ID | ord-bdeeaed94c8542f988f218988becbf56 |
|---|
| 出典メモ | uspto-grants-2008_04 |
|---|
