2-Amino-2-(tetrahydro-2H-pyran-4-YL)ethanol → 5-Cyano-1-(3-trifluoromethoxybenzyl)-1H-indole-2-carboxylic acid [2-hydroxy-1-(tetrahydropyran-4-yl)ethyl]amide

反応式

[C:1](#[N:2])[c:3]1[cH:4][c:5]2[cH:6][c:7]([C:24](=[O:25])[OH:26])[n:8]([CH2:12][c:13]3[cH:14][c:15]([O:19][C:20]([F:21])([F:22])[F:23])[cH:16][cH:17][cH:18]3)[c:9]2[cH:10][cH:11]1.[NH2:27][CH:28]([CH2:29][OH:30])[CH:31]1[CH2:32][CH2:33][O:34][CH2:35][CH2:36]1>>[C:1](#[N:2])[c:3]1[cH:4][c:5]2[cH:6][c:7]([C:24](=[O:26])[NH:27][CH:28]([CH2:29][OH:30])[CH:31]3[CH2:32][CH2:33][O:34][CH2:35][CH2:36]3)[n:8]([CH2:12][c:13]3[cH:14][c:15]([O:19][C:20]([F:21])([F:22])[F:23])[cH:16][cH:17][cH:18]3)[c:9]2[cH:10][cH:11]1

参加物

反応物 2

HCID 247297702-Amino-2-(tetrahydro-2H-pyran-4-YL)ethanol

HCID 685431065-cyano-1-(3-trifluoromethoxybenzyl)-1H-indole-2-carboxylic acid

生成物 1

HCID 866246415-Cyano-1-(3-trifluoromethoxybenzyl)-1H-indole-2-carboxylic acid [2-hydroxy-1-(tetrahydropyran-4-yl)ethyl]amide

出典と根拠

ORDレコード: ord-0523ac866b194ad98969cc7dbd36c28d
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…