2-Phenyl-4-methylpentylamine → N-(2-Chloro-3-trifluoromethylbenzyl)-2-phenyl-4-methylpentylamine

HRID 902749

反応式

HRID 902749 の反応式
[C:1]1([CH:7]([CH2:10][CH:11]([CH3:13])[CH3:12])[CH2:8][NH2:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Cl:14][C:15]1[C:33]([C:34]([F:37])([F:36])[F:35])=[CH:32][CH:31]=[CH:30][C:16]=1[CH2:17]NCC(C1C=CC(OC)=CC=1)C>>[Cl:14][C:15]1[C:33]([C:34]([F:35])([F:36])[F:37])=[CH:32][CH:31]=[CH:30][C:16]=1[CH2:17][NH:9][CH2:8][CH:7]([C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)[CH2:10][CH:11]([CH3:13])[CH3:12]

参加物

3

反応物 2

HCID 207282122-Phenyl-4-methylpentylamineHCID 69254854N-(2-Chloro-3-trifluoromethylbenzyl)-2-(4-methoxyphenyl)propylamine

生成物 1

HCID 69253156N-(2-Chloro-3-trifluoromethylbenzyl)-2-phenyl-4-methylpentylamine収率 77%

実験手順

The titled compound was prepared from 2-Phenyl-4-methylpentylamine in 77% yield in the same manner as the preparation of N-(2-Chloro-3-trifluoromethylbenzyl)-2-(4-methoxyphenyl)propylamine in Example 188d. MS (ESI) 370 (MH+)

出典と根拠

ORDレコード
ord-937f1ad24ce844b69975ae6c0e83d414
出典データセット
uspto-grants-2008_04
特許番号
US07365085B2

関連ノート

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