Benzoyl isothiocyanate → N-(1,3-Diphenyl-1H-pyrazol-5-yl)thiourea

反応式

[C:1]1([N:7]2[C:11]([NH2:12])=[CH:10][C:9]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)=[N:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C([N:27]=[C:28]=[S:29])(=O)C1C=CC=CC=1>>[C:1]1([N:7]2[C:11]([NH:12][C:28]([NH2:27])=[S:29])=[CH:10][C:9]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)=[N:8]2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

参加物

反応物 2

HCID 68284Benzoyl isothiocyanate

HCID 1999691,3-Diphenyl-1H-pyrazol-5-amine

生成物 1

HCID 12763850N-(1,3-Diphenyl-1H-pyrazol-5-yl)thiourea

実験手順

1,3-Diphenyl-5-amino pyrazole (117.5 g.) and benzoyl isothiocyanate (89.65 g.) were reacted as described in Example IV to give 119.8 g. of product, mp 198°-201° C.

後処理

customto give 119.8 g

出典と根拠

ORDレコード: ord-f56160388b3b424692daa09af61745c1
出典データセット: uspto-grants-1980_10
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04226773

反応ノート

読み込み中…