2-{[2-Chloro-4-(trifluoromethyl)phenyl]amino}-3-methylbutanoic acid → (6-Benzoyl-2-pyridyl)methyl 2-(2-chloro-4-trifluoromethylphenylamino)-3-methylbutanoate

HRID 903175

反応式

HRID 903175 の反応式
[Cl:1][C:2]1[CH:7]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:5]=[CH:4][C:3]=1[NH:12][CH:13]([CH:17]([CH3:19])[CH3:18])[C:14]([OH:16])=[O:15].[C:20]([C:28]1[N:33]=[C:32]([CH2:34]O)[CH:31]=[CH:30][CH:29]=1)(=[O:27])[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>>[Cl:1][C:2]1[CH:7]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:5]=[CH:4][C:3]=1[NH:12][CH:13]([CH:17]([CH3:19])[CH3:18])[C:14]([O:16][CH2:34][C:32]1[CH:31]=[CH:30][CH:29]=[C:28]([C:20](=[O:27])[C:21]2[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=2)[N:33]=1)=[O:15]

参加物

3

反応物 2

HCID 39476432-{[2-Chloro-4-(trifluoromethyl)phenyl]amino}-3-methylbutanoic acidHCID 20293448(6-Benzoyl-2-pyridyl)methanol

生成物 1

HCID 23337835(6-Benzoyl-2-pyridyl)methyl 2-(2-chloro-4-trifluoromethylphenylamino)-3-methylbutanoate

実験手順

Using the procedure of Example 1, the acid chloride of 2-(2-chloro-4-trifluoromethylphenylamino)-3-methylbutanoic acid is reacted with (6-benzoyl-2-pyridyl)methanol to yield (6-benzoyl-2-pyridyl)methyl 2-(2-chloro-4-trifluoromethylphenylamino)-3-methylbutanoate, MS m/e 490 (M+).

出典と根拠

ORDレコード
ord-3eff78d748f742d08b2b2ad132e02c3c
出典データセット
uspto-grants-1980_10
特許番号
US04226872

関連ノート

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