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Dimethylamine → [(2-Chloro-6-fluoro-phenyl)-(2-phenyl-1H-indol-3-yl)-methyl]-dimethylamine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Dimethylamine | HCID 674 | — |
| 反応物 | 2-Phenylindole | HCID 13698 | — |
| 反応物 | 2-Chloro-6-fluorobenzaldehyde | HCID 67847 | — |
| 反応物 | (2-Chloro-6-fluoro-benzylidene)-dimethylammonium chloride | HCID 21985312 | — |
| 生成物 | [(2-Chloro-6-fluoro-phenyl)-(2-phenyl-1H-indol-3-yl)-methyl]-dimethylamine | HCID 21985288 | — |
反応手順
The preparation was carried out in accordance with general synthesis instructions 4 from 2-phenylindole and (2-chloro-6-fluoro-benzylidene)-dimethyl-ammonium chloride, which had been prepared in accordance with example 24 from 2-chloro-6-fluoro-benzaldehyde and dimethylamine.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07091220B2 |
| 出典データセット | uspto-grants-2006_08 |
| ORD ID | ord-ab06589450384aad9d4c3c244b329c3c |
| 出典メモ | uspto-grants-2006_08 |