化工社化工社 化学情報印刷レポート · 研究参考用
Isopropylamine → N-Isopropylmethacrylamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Isopropylamine | HCID 6363 | — |
| 反応物 | Methyl Methacrylate | HCID 6658 | — |
| 触媒 | 2-Propanamine, hydrochloride (1:1) | HCID 6432137 | — |
| 生成物 | N-Isopropylmethacrylamide | HCID 83698 | 69.5% |
反応手順
500 g (5 mols) of methyl methacrylate, 325 g (5.5 mols) of isopropylamine, and 12.4 g (0.13 mol) of isopropylamine hydrochloride were reacted in the presence of 0.03 mol of ferric acetylacetonate for 21/2 hours in a steel autoclave at 220° C. The pressure increased to a maximum of 18 atmospheres. The methyl methacrylate reacted to the extent of 80% and gave 442 g of N-isopropylmethacrylic acid amide (corresponding to a 68% yield referred to the methyl methacrylate used).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04228102 |
| 出典データセット | uspto-grants-1980_10 |
| ORD ID | ord-b6193f641d56497c9298501d403d530e |
| 出典メモ | uspto-grants-1980_10 |