HCID 70596364、化合物 → 2-(p-Biphenylyl)-2-penten-4-one

HRID 903526ノート

反応式

HRID 903526 の反応式
[C:1]1([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7](O)([CH3:12])[CH2:8][C:9](=[O:11])[CH3:10]>CO.O>[C:1]1([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7](=[CH:8][C:9](=[O:11])[CH3:10])[CH3:12]

参加物

4

反応物 1

HCID 70596364HCID 70596364、化合物

生成物 1

HCID 545652342-(p-Biphenylyl)-2-penten-4-one

試薬・触媒・溶媒 2

HCID 887Methanol溶媒HCID 962Water溶媒

反応条件

温度
75 °C

実験手順

To a 70° C. warm solution of 104.2 g 4-(p-biphenylyl)-4-hydroxypentan-2-one in a mixture of 450 ml methanol and 80 ml water 206 g ca. 65% sulphuric acid is added dropwise and the mixture is stirred 21/2 hours at 75° C. After cooling to 25° C. the resulting solid is filtered off, washed with water, then with diluted sodium hydroxide solution, again with water, dried and then recrystallised from toluene to give the title compound, m.p. 134°-136° C.

後処理

  1. additionis added dropwise
  2. temperatureAfter cooling to 25° C. the resulting solid
  3. filtrationis filtered off
  4. washwashed with water
  5. dry with materialwith diluted sodium hydroxide solution, again with water, dried
  6. customrecrystallised from toluene

出典と根拠

ORDレコード
ord-17212dc0cefb4574add172e9b68bccb9
出典データセット
uspto-grants-1980_10
特許番号
US04228105

反応ノート

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