Urea → Tetrakis(ureidomethyl)phosphonium chloride

反応式

[CH2:1]([P+:3]([CH2:8]O)([CH2:6]O)[CH2:4]O)O.[Cl-:10].[NH2:11][C:12]([NH2:14])=[O:13]>>[Cl-:10].[NH:11]([CH2:8][P+:3]([CH2:1][NH:11][C:12]([NH2:14])=[O:13])([CH2:4][NH:11][C:12]([NH2:14])=[O:13])[CH2:6][NH:11][C:12]([NH2:14])=[O:13])[C:12]([NH2:14])=[O:13]

参加物

反応物 2

HCID 1176Urea

HCID 31298Tetrakis(hydroxymethyl)phosphonium chloride

生成物 1

HCID 23463266Tetrakis(ureidomethyl)phosphonium chloride収率 100.9%

実験手順

Reaction of 80% THPC (23.82 g, 0.1 mol) with urea (24.02 g, 0.4 mol), following Example 3, gave 36.18 g (100.8%) of tetrakis(ureidomethyl)phosphonium chloride (I, R=R'=R"=H, X=Cl) as a colorless, brittle glass, identical (31P NMR) to the product of Example 11.

出典と根拠

ORDレコード: ord-3bc40ace047f41f4a5191a8aa1c9e2ea
出典データセット: uspto-grants-1980_10
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04228100

反応ノート

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