関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Methyltryptamine | HCID 6088 | — |
| 反応物 | Glutaric anhydride | HCID 7940 | — |
| 溶媒 | Benzene | HCID 241 | — |
| 生成物 | N-methyl-N-(4-carboxybutyryl)-tryptamine | HCID 23336462 | 90% |
反応手順
8.70 g of N-methyl-tryptamine (i.e., 3-(2-methylaminoethyl)-indole) were dissolved in 100 ml of benzene, and 5.7 g of glutaric acid anhydride were added thereto. The mixture was stirred at 80° C. for 3 hours. After the reaction was completed, the mixture was evaporated to remove solvent. 12.0 g of N-methyl-N-(4-carboxybutyryl)-tryptamine (i.e., 3-[2-(N-methyl-4-carboxybutanamido)ethyl]-indole) were thereby obtained. Yield: 90%
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04228168 |
|---|
| 出典データセット | uspto-grants-1980_10 |
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| ORD ID | ord-6b474e5ee71e4eaa9c615e16d4c3b8f5 |
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| 出典メモ | uspto-grants-1980_10 |
|---|
