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Phenolphthalein → (-)-alpha-Amino-4-hydroxy-3-(methoxymethyl)benzeneacetic acid methyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Phenolphthalein | HCID 4764 | — |
| 反応物 | Potassium Hydroxide | HCID 14797 | — |
| 反応物 | (-)-alpha-Amino-4-hydroxy-3-(methoxymethyl)benzeneacetic acid methyl ester hydrochloride | HCID 70585116 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | (-)-alpha-Amino-4-hydroxy-3-(methoxymethyl)benzeneacetic acid methyl ester | HCID 53644499 | — |
反応手順
(-)-α-Amino-4-hydroxy-3-(methoxymethyl)benzeneacetic acid methyl ester hydrochloride is dissolved in a minimum amount of methanol. To this solution is added methanolic potassium hydroxide until a basic reaction to phenolphthalein is observed. The potassium chloride which precipitates is removed and the solvent is removed under vacuum to give a quantitative yield of the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04229363 |
| 出典データセット | uspto-grants-1980_10 |
| ORD ID | ord-677af14c299d4a7082676fdb10894b4a |
| 出典メモ | uspto-grants-1980_10 |