化工社化工社 化学情報印刷レポート · 研究参考用
2-Oxobutanoic Acid → Thiazolidinecarboxylic acid, 2-ethyl-
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Oxobutanoic Acid | HCID 58 | — |
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | Cysteamine Hydrochloride | HCID 9082 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | Thiazolidinecarboxylic acid, 2-ethyl- | HCID 198462 | 65.8% |
反応手順
11.4 g of cysteamine hydrochloride and 10.1 g of triethylamine were dissolved in 100 ml of ethanol, to which was added 10.2 g of 2-keto-butyric acid. The mixture was refluxed for 30 minutes, cooled and filtered thereby giving 10.6 g (yield 65.7%) of 2-ethyl-thiazolidine-2-carboxylic acid with a melting point of 235°-238° C. (decomposed).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04229461 |
| 出典データセット | uspto-grants-1980_10 |
| ORD ID | ord-6417e3b5d0cb4c31933f5935b2dc8ca2 |
| 出典メモ | uspto-grants-1980_10 |