Dimethylamine → [(2-Chloro-4-fluoro-phenyl)-(4-nitro-1H-indol-3-yl)-methyl]-dimethyl-amine

HRID 9043

反応式

HRID 9043 の反応式
[N+:1]([C:4]1[CH:12]=[CH:11][CH:10]=[C:9]2[C:5]=1[CH:6]=[CH:7][NH:8]2)([O-:3])=[O:2].[Cl-].[Cl:14][C:15]1[CH:24]=[C:23]([F:25])[CH:22]=[CH:21][C:16]=1[CH:17]=[N+:18]([CH3:20])[CH3:19].ClC1C=C(F)C=CC=1C=O.CNC>>[Cl:14][C:15]1[CH:24]=[C:23]([F:25])[CH:22]=[CH:21][C:16]=1[CH:17]([N:18]([CH3:20])[CH3:19])[C:6]1[C:5]2[C:9](=[CH:10][CH:11]=[CH:12][C:4]=2[N+:1]([O-:3])=[O:2])[NH:8][CH:7]=1

参加物

5

反応物 4

HCID 674DimethylamineHCID 1450242-Chloro-4-fluorobenzaldehydeHCID 1457664-Nitro-1H-indoleHCID 21985315(2-Chloro-4-fluoro-benzylidene)-dimethylammonium chloride

生成物 1

HCID 21985305[(2-Chloro-4-fluoro-phenyl)-(4-nitro-1H-indol-3-yl)-methyl]-dimethyl-amine

実験手順

The preparation was carried out in accordance with general synthesis instructions 4 from 4-nitroindole and (2-chloro-4-fluoro-benzylidene)-dimethyl-ammonium chloride, which had been prepared in accordance with example 24 from 2-chloro-4-fluoro-benzaldehyde and dimethylamine.

出典と根拠

ORDレコード
ord-c5d9bebb04b040e391a8be4021bce133
出典データセット
uspto-grants-2006_08
特許番号
US07091220B2

関連ノート

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